October 23, 2021
Health

First Human Trial Of Coronavirus Vaccine To Begin Today

A clinical trial to test a coronavirus vaccine is set to begin today Monday, according to a US government official.

The first human participant will receive an experimental dose to test for potential side effects, but they will not actually be infected with the Covid-19 virus, the anonymous official told the Associated Press.

The National Institutes of Health is funding the trial, which is taking place at the Kaiser Permanente Washington Health Research Institute in Seattle.

Public health officials say it will take a year to 18 months to fully validate any potential vaccine.

Testing will begin with 45 young, healthy volunteers with different doses of shots co-developed by NIH and Moderna Inc.

Nurses discuss before testing patients for coronavirus at the University of Washington Medical Center in Seattle (Picture: John Moore/Getty Images)

There’s no chance participants could get infected from the shots, because they don’t contain the virus itself.

The goal is purely to check that the vaccines show no worrisome side effects, setting the stage for larger tests.

Dozens of research groups around the world are racing to create a vaccine as Covid-19 cases continue to grow. Importantly, they’re pursuing different types of vaccines.

Shots developed from new technologies that not only are faster to produce than traditional inoculations but might prove more potent.

Some researchers even aim for temporary vaccines, such as shots that might guard people’s health a month or two at a time while longer-lasting protection is developed.

A nurse wearing protective clothing handles a potentially infected coronavirus swab at a drive-by testing centre (Picture: John Moore/Getty Images)

Meanwhile, Inovio Pharmaceuticals aims to begin safety tests of its vaccine candidate next month in a few dozen volunteers at the University of Pennsylvania and a testing centre in Kansas City, Missouri, followed by a similar study in China and South Korea.

Dr Anthony Fauci, director of NIH’s National Institute of Allergy and Infectious Diseases, cautioned that even if initial safety tests go well, ‘you’re talking about a year to a year and a half’ before any vaccine could be ready for widespread use.

That still would be a record-setting pace. It can take a long time because it takes additional studies of thousands of people to tell if a vaccine truly protects and does no harm, but manufacturers know the wait will be hard for a frightened public.

President Donald Trump has been pushing for swift action on a vaccine, saying in recent days that the work is ‘moving along very quickly’ and he hopes to see a vaccine ‘relatively soon’.

Today, there are no proven treatments. In China, scientists have been testing a combination of HIV drugs against the new coronavirus, as well as an experimental drug named remdesivir that was in development to fight Ebola.

In the US, the University of Nebraska Medical Center also began testing remdesivir in some Americans who were found to have Covid-19 after being evacuated from a cruise ship in Japan.

For most people, the new coronavirus causes only mild or moderate symptoms, such as fever and cough. For some, especially older adults and people with existing health problems, it can cause more severe illness, including pneumonia.

The worldwide outbreak has sickened more than 156,000 people and left more than 5,800 dead. The death toll in the UK stands at 35 while more than 1,300 have been infected.



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